|
Home >> Health >> Conditions and Diseases >> Eye Disorders >> Microphthalmia |
|
Microphthalmia means little eyes. Around mammals the failure of expression of the transcription factor, MITF (microphthalmia-associated transcription factor), in the pigmented retina prevents this structure from fully differentiating. This successively is the causal agent of the malformation of the choroid fissure of the eye, resulting in the drain of vitreous humor fluid. Forgoing this fluid, a eye fails to enlarge, so a title microphthalmia. [http://www.ncbi.nlm.nih.gov] A cistron encoding a microphthalmia-associated transcription factor (Mitf) occurs as member of the basic helix-loophelix-leucine zipper (bHLH-ZIP) personal. Waardenburg syndrome nature and severity Two (WS nature and severity Two)within homo is likewise the nature and severity of microphthalmia syndrome. Mutation in MITF gene come thought to exist as responsible this syndrome. A human being MITF cistron is homologous to the mouse MITF cistron (aka mouse mi or even microphthalmia cistron); mouse with mutations in this factor come hypopigmented in their fur. | |
|
International Children's Anophthalmia Network (ICAN) Parent support group for families with a child with anophthalmia or microphthalmia. Micro and Anopthalmic Children's Society (MACS) Provides support and information for parents and professionals with microphthalmia, anophthalmia, coloboma and related conditions. Noeyes.com Story and updates of a baby born without eyes. A Singular View The author explains how Microphthalmia has affected her son. Franchesca's Microphthalmia Page Franchesca is a teenager with anophthalmia. Here she, her mother, and a friend share their thoughts. National Eye Institute - Anophthalmia and Microphthalmia Provides patient information about this rare eye disorder, including causes, treatment and additional resources. Microptalmia - A True Story Describes a case of Microphtalmia in the Netherlands. |
|
© 2005 GeneralAnswers.org